2025, Vol. 9 Issue 3, Part BPages: 126-131
Precocious Puberty: A Comparative and Integrative Review of Unani and Modern Medical Perspectives
Bhatti Afira Khanam, Khaikasha Shaheen, Shahazadi Sultana and Syeda Abidunissa
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Abstract:
Precocious puberty refers to the premature onset of secondary sexual characteristics before eight years in girls and nine years in boys. It represents a deviation from the natural rhythm of growth and development described in both Unani and modern medical systems. Classical Unani scholars such as Ibn Sina, Al-Razi, Jurjani, and others identified similar conditions though they did not use the modern term, attributing early maturity to excessive innate heat (Ghalabat-e-Harārat-e-Gharīziyya) and imbalance of temperament (Sue Mizaj). Modern endocrinology associates the condition with premature activation of the hypothalamic–pituitary–gonadal (HPG) axis, obesity, and exposure to endocrine-disrupting chemicals. This review explores conceptual parallels, etiological mechanisms, and management approaches across both traditions. Integrating Unani theories of temperament regulation with evidence-based endocrine management offers a holistic approach to prevention and therapy. Unani regimens emphasizing Ilaj bil Ghiza (dietary regulation), Ilaj bil Dawa (pharmacotherapy), and Ilaj bil Tadbeer (regimental therapy) align conceptually with lifestyle modification, hormonal regulation, and psychosocial support in modern practice.