Vol. 9, Issue - 1, Part B (2025)

The most prevalent endocrine disorder affecting women of reproductive age is polycystic ovarian disease (PCOD), which is also the leading cause of anovulation-induced infertility. Five to ten percent of women of reproductive age have PCOD, and the percentage rises to fifteen percent among infertile women. This illness has been explained by renowned Unani physician in the classical literature under the areas of liver problems, phlegmatic illness, obesity, and amenorrhea. Various medical options are used to treat subfertility associated with polycystic ovarian disease. This narrative review was conducted to provide an update and summarize the available evidence on management of polycystic ovarian disease related to infertility. A wide literature search was performed and preferably randomized controlled trial are included. Management is centred on lifestyle changes and Unani pharmacological ovulation induction.

Lastly, we describe the present and upcoming approaches to treating this prevalent ailment in women. The primary foundation of the Unani idea of PCOD is the predominance of khilt-e-balgham, or phlegm. Phlegm production has been linked to the main symptoms of PCOD, including obesity, oligomenorrhea, and amenorrhea. Therefore, it is asserted that PCOD results from the body's preponderance of phlegm, which causes obesity, amenorrhea, and ovarian cyst formation. This condition is complicated since it can lead to consequences such as endometrial and breast cancer, metabolic syndrome, type 2 diabetes, infertility, and cardiovascular diseases. There is now no effective treatment for this complex illness, and patients typically receive only symptomatic care with hormones and insulin sensitizers before developing a medication dependence.

In this case study, we will look at an Unani approach in the management of Infertility with Polycystic Ovarian Disease. We also go over new data about herbal medications' impact on insulin resistance in PCOD.