Vol. 9, Issue - 1, Part A (2025)

2025, Vol. 9 Issue 1, Part APages: 08-13

Exploring the safety profile of Doronicum hookeri: Insights and findings

Fazlurrehman, Nazish Siddiqui, Sumbul Rehman and Sumera Sagheer
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Abstract:
Background: Herbal medicines play a crucial role in traditional healthcare systems. According to the World Health Organization (WHO), an estimated 70-80% of the global population depends on traditional remedies for their health needs. These herbs are widely utilized for the treatment and prevention of various health conditions. However, the increasing popularity of herbal products has raised concerns about their safety. Despite being considered safe due to their natural origins, there have been cases of toxicity and adverse effects. The WHO emphasizes the importance of conducting safety evaluations for herbal medicines and food products to identify potential risks associated with environmental or soil contaminants.
Methods: Plants are susceptible to contamination by harmful substances. In this study, the safety profile of Doronicum hookeri (Darunaj Aqrabi) from the Asteraceae family was assessed by evaluating microbial load, heavy metal content using Inductively coupled plasma mass spectrometry (ICPMS), aflatoxins through Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS), and pesticide residues via Gas Chromatography-Tandem Mass Spectrometry (GC-MS/MS).
Results: The analysis showed that the levels of heavy metals, including lead, cadmium, mercury, and arsenic, were within the acceptable limits set by WHO standards. Additionally, no aflatoxins, pesticide residues, or microbial contamination were found in the crude drug sample.
Conclusion: The safety evaluation demonstrates that Doronicum hookeri (Darunaj Aqrabi) is safe for use, with no indication of toxicity or associated risks.


International Journal of Unani and Integrative Medicine
How to cite this article:
Fazlurrehman, Nazish Siddiqui, Sumbul Rehman, Sumera Sagheer. Exploring the safety profile of Doronicum hookeri: Insights and findings. Int J Unani Integ Med 2025;9(1):08-13. DOI: 10.33545/2616454X.2025.v9.i1a.315
 
International Journal of Unani and Integrative Medicine
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