Vol. 8, Issue - 1, Part A (2024)

Bushra Sabir, Iqra Hashmi and MN Khan

DOI: https://doi.org/10.33545/2616454X.2024.v8.i1a.252

Abstract:
Nephrotic syndrome (NS) is a glomerular disorder characterized by significant proteinuria, hypoalbuminemia, hyperlipidemia, and edema, often resulting from increased permeability of the damaged renal glomerular basement membrane. Nephrotic pattern resembles to Du’f al-Kulya Barid in Unani medical literature. It's condition in which feathers don't perform their normal functions because of impairment in their disposition in their humoral status or anomalies in their structure due to ascendance of Barudat (Dispassionateness) in order. This case study focuses on a 52-year-old female diagnosed with idiopathic nephrotic syndrome, highlighting her clinical presentation, conventional treatment with steroids, and subsequent management with Unani medicine. The patient, dissatisfied with allopathic therapy, sought treatment at the Central Research Institute of Unani Medicine, Lucknow. The prescribed Unani regimen included various herbal formulations targeting liver and kidney functions. The patient's progress was monitored through clinical examinations and biochemical assessments over a three-month period. The results revealed significant improvements in laboratory parameters, including reduced urea, creatinine, and uric acid levels, as well as the resolution of edema and other symptoms. The Unani treatment utilized medications such as Sharbat Buzoori Moatadil, Majoon Dabeed ul Ward, Arq kasni and Jawarish Jalinoos, known for their diuretic, anti-inflammatory, and general tonic properties. The patient's response suggests the potential efficacy of Unani formulations in managing nephrotic syndrome. However, further research is warranted to explore the pharmacokinetics and pharmacodynamics of these formulations for a comprehensive understanding of their therapeutic effects. This case underscores the importance of integrating traditional medical approaches for improved and safe management of nephrotic syndrome.