Mohd. Aleemuddin Quamri, Shabana Begum, MA Siddiqui and Md. Anzar Alam
Abstract:Background and objectives:
Diabetes mellitus is characterized by elevated blood glucose, it can leads to serious vascular complications with poor prognosis. Dyslipidemia secondary to DM is one of the aggravating risk factor for cardiovascular diseases. In Unani system of medicine Diabetes associated Dyslipidemia has been treating with several potent anti-hyperglycemic and anti-dyslipidemic single drugs. To evaluate the effect of Kanduri (Coccinia indica
) among patients of Dyslipidemia associated with type II Diabetes mellitus this study is conducted.
Methods: A single blind, randomized, standard control clinical trial on patients of Dyslipidemia secondary to Diabetes Mellitus Type II was conducted by randomly allocating the patients into two groups viz test (n=20) and control group (n=20) for a period of 8 weeks. Test group received 7.5 gram powder of dried leaves of Kanduri and control group received Tablet Metformin SR 500 mg. Both groups recieved drugs twice a day orally before meals.The study outcome was assessed with the difference in the objective findings of pre and post treatment.
Results: Objective parameters like TC, TGL, LDL, HDL were found insignificant, applying tests were paired t test, Wilcoxon matched pair test and Friedman test for intra group comparison and one way ANOVA and Kruskal- Wallis test with Dunn’s multiple pair comparison for inter group comparison with p>0.05.
Interpretation & Conclusion: This comparative trial revealed that interventions of both groups have no effect on Dyslipidemia associated with DM type II, however, the both the drugs were found to be free from any adverse effects.